Our new Apparent+ tissue clearing technique is the sole strategy that delipidates samples without improve in morphology and with minimal impact on structural integrity.

Megatome is a vibrating microtome created to area a wide choice of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With superior blade vibrating frequency and minimized blade deflection, Megatome enables higher-throughput tissue sectioning with uniform surface area profile, and also small tissue problems and knowledge loss.

Antibodies could get weeks to diffuse by means of just a few millimeters of tissue, using a steep labeling gradient from surface area to Main.

Megatome is suitable for precision: the blade vibrates at the next frequency and bigger amplitude vary than other microtomes, and encompasses a one of a kind deflection Command system.

Clone the task or get the most recent release. Functioning the utility will range a tad dependant upon how you retrieve the project.

Our preformulated EasyIndex Alternative raises and homogenize the refractive index of delipidated tissue samples, rendering them thoroughly transparent. This enables light penetration into your sample and makes certain the acquisition of large-resolution, in-concentrate image knowledge.

Megatome is really a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with small tissue damage and information reduction.

It’s the perfect time to update your microtome to Megatome. With exact substantial-frequency slicing for an unmatched range of sample dimensions and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied programs.

Thoroughly delipidate entire mouse brains or comparably sized samples in only one working day with SmartBatch+, or in one 7 days with our passive clearing kit.

Docset development requires at bare minimum two options: the title of the docset megatomi.com and The placement of your Javadoc information to incorporate inside the docset.

This could create a docset named Sample in The present Listing. Docset creation might be custom made with optional arguments:

Either obtain a launch or make a distribution zip as outlined over. Unzip the archive to your wished-for place.

Leverage the Apparent+ tissue clearing technique, as well as eFLASH and patented stochastic electrotransport systems, to quickly very clear and label total organs. Vital highlights and attributes contain:

Our novel Defend tissue preservation technique types intramolecular bonds employing polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.